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high school cohort study demonstrated that e-cigarette use was significantly associated with subsequent initiation of combustible cigarette smoking, while the reverse relationship was not observed ( Nicotine's reinforcing properties are thought to prime the brain's reward circuitry, enhancing susceptibility to other addictive behaviors

Potential confounds The major problem with assuming that PCSE causes these detrimental outcomes is that there is a number of confounding factors that might account for the association

Lifestyle and Subculture Influence Historically, clove cigarettes have held popularity in artistic, nightlife, and alternative communities

"Clearly, there needs to be greater awareness and management of the health risks associated with burning incense in indoor environments," said Rong Zhou of the South China University of Technology, in a statement to the press